The Harbour Hotel & Spa in Richmond, West London, was the site of a blaze which 100 firefighters attended on Tuesday evening.
London Fire Brigade said it was facing “challenging conditions” as it attempted to put the fire out.
The hotel features 76 bedrooms and three meeting/event rooms. According to the London Fire Brigade website, a leisure complex, pool building and part of the third floor were damaged in the fire.
Station manager Mike Cotton said: “The fire is in an annexe building and has been producing a lot of smoke.
“We would urge residents and businesses in the immediate area to keep windows and doors closed while we continue to tackle the fire.”
There were no reports of any injuries.
